货号 |
bs-3906R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-HSD3B1 antibody |
中文名称 |
Rabbit Anti-HSD3B1 antibody |
研究领域 |
肿瘤,细胞生物,免疫学 |
英文别名 |
3 beta and steroid delta isomerase 1; 3 beta and steroid hydroxy delta 5 steroid dehydrogenase; 3 beta HSD I; 3BH; 3BHSD; HGNC:5217; HSD3B; HSD3B1; HSDB3; HSDB3A; Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1; Hydroxy delta 5 |
反应物种(已验证) |
Mouse,Rat |
反应物种(预测) |
Human,Dog,Cow,Horse |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
WB,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
41 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human HSD3B1 |
抗原表位 |
301-373/373 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. |
Tissue |
Placenta and skin. Predominantly expressed in mammary gland tissue. |
SIMILARITY |
Belongs to the 3-beta-HSD family. |
SWISS |
P14060 |
Gene ID |
3283 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] |