货号 |
bs-1847R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-MAP1A antibody |
中文名称 |
Rabbit Anti-MAP1A antibody |
研究领域 |
肿瘤,细胞生物,免疫学,神经生物学,信号转导,细胞凋亡,激酶和磷酸酶 |
英文别名 |
MAP 1A; MAP-1A; MTAP1A; MAP 1L; MAP1L; MAP1A heavy chain; Map1a; MAP1A_HUMAN; Microtubule associated protein 1 like; Microtubule Associated Protein 1A; Microtubule-associated protein 1A; MTAP1A; Proliferation related protein p80; Proliferation-related pro |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse,Chicken,Dog,Pig,Cow,Horse |
产品应用(已验证) |
IHC,FCM |
产品应用(可推荐) |
IF |
推荐稀释比例 |
IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=1μg /test,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
326 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human MAP1A heavy chain |
抗原表位 |
2651-2750/3014 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm, cytoskeleton (Probable). |
Tissue |
Brain |
SIMILARITY |
Belongs to the MAP1 family. |
SUBUNIT |
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with TIAM2. Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG4. Binds to CSNK1D. |
Function |
Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements. |
Post-translational |
Phosphorylated by CSNK1D.
LC2 is generated from MAP1A by proteolytic processing. |
SWISS |
P78559 |
Gene ID |
4130 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008] |