货号 |
bs-0337R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Myelin Protein Zero antibody |
中文名称 |
Rabbit Anti-Myelin Protein Zero antibody |
研究领域 |
神经生物学,信号转导 |
英文别名 |
peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein;
CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN. |
反应物种(已验证) |
Mouse,Rat,Dog |
反应物种(预测) |
Human,Pig,Cow,Horse,Rabbit,GuineaPig |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
24 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human P0 protein |
抗原表位 |
175-248/248 |
抗原细胞定位 |
Cytoplasmic |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell membrane; Single-pass type I membrane protein. |
Tissue |
Found only in peripheral nervous system Schwann cells. |
SIMILARITY |
Belongs to the myelin P0 protein family. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
SUBUNIT |
Homodimer and homotetramer. |
SWISS |
P25189 |
Gene ID |
4359 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein. |