货号 |
bs-1373R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Lipocalin 2/NGAL antibody |
中文名称 |
Rabbit Anti-Lipocalin 2/NGAL antibody |
研究领域 |
肿瘤,细胞生物,神经生物学,信号转导,细胞凋亡,激酶和磷酸酶 |
英文别名 |
Lipocalin 2; Neutrophil Gelatinase associated Lipocalin; 25 kDa alpha 2 microglobulin related subunit of MMP9; Alpha 2 microglobulin related protein; HGNC:6526; HNL; Lcn 2; LCN-2; Lcn2; Neutrophil gelatinase associated lipocalin precursor; NGAL; Oncogene |
反应物种(已验证) |
Human |
反应物种(预测) |
Mouse,Rat,Dog,Pig,Cow,Rabbit |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
20 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Lipocalin 2 |
抗原表位 |
101-198/198 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. Note=Upon binding to the SLC22A17 (24p3R) receptor, it is internalized. |
Tissue |
Expressed in bone marrow and in tissues that are prone to exposure to microorganism. High expression is found in bone marrow as well as in uterus, prostate, salivary gland, stomach, appendix, colon, trachea and lung. Not found in the small intestine or pe |
SIMILARITY |
Belongs to the calycin superfamily. Lipocalin family. |
SUBUNIT |
Homodimer; disulfide-linked. Heterodimer; disulfide-linked with MMP9. |
Function |
Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial en |
SWISS |
P80188 |
Gene ID |
3934 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Lipocalin 2 is a member of the lipocalin family which encompass more than 25 members (including proteins like retinol binding protein, a1 microglobulin, b lactoglobulin, apolipoprotein D and odorant binding protein). The members of the lipocalin family are characterized by their ability to bind small lipophilic substances in their hydrophobic core, and thereby serve as transporters of substances. |