货号 |
bs-2772R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-KLF2 antibody |
中文名称 |
Rabbit Anti-KLF2 antibody |
研究领域 |
肿瘤,细胞生物,信号转导,转录调节因子 |
英文别名 |
Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2 (lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUMAN; Krueppel-like factor 2; Lklf; Lung krueppel like fa |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
WB,IHC,IF,FCM |
推荐稀释比例 |
WB=1:100-500,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=1:ug/Test,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
37 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human KLF2 |
抗原表位 |
251-355/355 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. |
SIMILARITY |
Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
SUBUNIT |
Interacts with WWP1. |
Function |
Binds to the CACCC box in the beta-globin gene promoter and activates transcription . |
Post-translational |
Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. |
SWISS |
Q9Y5W3 |
Gene ID |
10365 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011] |