货号 |
bs-9606R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-RBM20 antibody |
中文名称 |
Rabbit Anti-RBM20 antibody |
研究领域 |
心血管,转录调节因子 |
英文别名 |
Probable RNA-binding protein 20; Rbm20; RBM20_HUMAN; RNA-binding motif protein 20. |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Dog,Cow,Horse,Sheep |
产品应用(已验证) |
WB,FCM |
产品应用(可推荐) |
IHC,ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=3ug/test,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
134 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human RBM20 |
抗原表位 |
361-460/1227 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus (By similarity). |
Tissue |
Expressed in the heart. |
SIMILARITY |
Contains 1 RRM (RNA recognition motif) domain. |
Function |
RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin). |
DISEASE |
Defects in RBM20 are the cause of cardiomyopathy dilated type 1DD (CMD1DD) [MIM:613172]. A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of prematu |
SWISS |
Q5T481 |
Gene ID |
282996 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a protein that likely binds RNA. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Mar 2010] |