货号 |
bs-8538R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-EP4 antibody |
中文名称 |
Rabbit Anti-EP4 antibody |
研究领域 |
信号转导,G蛋白偶联受体, |
英文别名 |
Prostaglandin E Receptor EP4; EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Bee |
产品应用(已验证) |
WB |
产品应用(可推荐) |
IHC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
53 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human EP4R/Prostaglandin E Receptor EP4 |
抗原表位 |
151-250/488 |
抗原细胞定位 |
Extracellular |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell membrane. |
Tissue |
High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. |
SIMILARITY |
Belongs to the G-protein coupled receptor 1 family. |
SUBUNIT |
Interacts with FEM1A. |
Function |
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial t |
Post-translational |
Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. |
SWISS |
P35408 |
Gene ID |
5734 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |