货号 |
bs-6038R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-CRABP2 antibody |
中文名称 |
Rabbit Anti-CRABP2 antibody |
研究领域 |
肿瘤,细胞生物,染色质和核信号,信号转导 |
英文别名 |
Cellular retinoic acid binding protein 2; Cellular retinoic acid binding protein II; CRABP II; CRABPII; CRABP 2; CRABP-2; RBP6; RABP2_HUMAN. |
反应物种(已验证) |
Mouse,Rat |
反应物种(预测) |
Human,Dog,Pig,Cow,Rabbit,GuineaPig |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
16 |
细胞定位 |
细胞核,细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human CRABP2 |
抗原表位 |
51-138/138 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. Endoplasmic reticulum. Nucleus. |
SIMILARITY |
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
SUBUNIT |
Interacts with RXR and RARA. Interacts with importin alpha. |
Function |
Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
Post-translational |
Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |
SWISS |
P29373 |
Gene ID |
1382 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. |