货号 |
bs-3461R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Phospho-PPIG (Ser376) antibody |
中文名称 |
Rabbit Anti-Phospho-PPIG (Ser376) antibody |
产品标签 |
磷酸化抗体 |
研究领域 |
细胞生物,免疫学,染色质和核信号 |
英文别名 |
CARS cyclophilin; CARS Cyp; CASP 10; CASP10; Clk associating RS cyclophilin; Cyclophilin G; CyclophilinG; CYP; MGC133241; Peptidyl prolyl cis trans isomerase G; Peptidyl prolyl isomerase G; Peptidylprolyl isomerase G (cyclophilin G); Peptidylprolyl isomer |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Chicken,Dog,Pig,Cow,Horse,Sheep |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
89 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated Synthesised phosphopeptide derived from human PPIG around the phosphorylation site of Ser376 |
抗原表位 |
VS(p-S)GE |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus matrix. Nucleus speckle. Note=Colocalizes with RNA splicing factors at nuclear speckles. |
Tissue |
Ubiquitous. |
SIMILARITY |
Contains 1 PPIase cyclophilin-type domain. |
SUBUNIT |
Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II. |
Function |
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of p |
Post-translational |
Phosphorylated upon DNA damage, probably by ATM or ATR. |
SWISS |
Q13427 |
Gene ID |
9360 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
PPIG belongs to the the peptidyl-prolyl cis/trans isomerase protein family (PPIases). PPIases accelerate the folding of proteins. PPIG catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and is implicated in the folding, transport, and assembly of proteins. It is distributed in nuclear speckles, a nuclear compartment rich in splicing factors, and colocalizes with the splicing factors SC35 and pinin, suggesting a role in the regulation of pre-mRNA splicing. |