货号 |
bs-11228R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Phospho-JunB (Thr102 + Thr104) antibody |
中文名称 |
Rabbit Anti-Phospho-JunB (Thr102 + Thr104) antibody |
产品标签 |
磷酸化抗体 |
研究领域 |
肿瘤,转录调节因子,激酶和磷酸酶 |
英文别名 |
Phospho-JunB (Thr102/Thr104); P-JunB (Phospho Thr102/Thr104); JUNB_HUMAN; Transcription factor JunB; Transcription factor jun B; Transcription factor AP-1 subunit JunB; Jun B; |
反应物种(已验证) |
Mouse |
反应物种(预测) |
Human,Rat,Pig,Cow,Horse,GuineaPig |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
WB,ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
38 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated Synthesised phosphopeptide derived from human JunB around the phosphorylation site of Thr102/Thr104 |
抗原表位 |
TT(p-T)P(p-T)PP |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. |
SIMILARITY |
Belongs to the bZIP family. Jun subfamily. Contains 1 bZIP (basic-leucine zipper) domain. |
SUBUNIT |
Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). |
Function |
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. |
Post-translational |
Ubiquitinated by ITCH, leading to its degradation. |
SWISS |
P17275 |
Gene ID |
3726 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'. |