货号 |
bs-20429R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-phospho-APG4B (Ser34) antibody |
中文名称 |
Rabbit Anti-phospho-APG4B (Ser34) antibody |
产品标签 |
磷酸化抗体 |
研究领域 |
肿瘤,细胞生物,信号转导,细胞凋亡 |
英文别名 |
APG4B (phospho-Ser34); APG4B (phospho Ser34); APG4B (phospho S34); APG4B (p-Ser34); p-APG4B (Ser34); APG4B; ATG4 autophagy related 4 homolog B (S. cerevisiae); AUT like 1 cysteine endopeptidase; AUTL1; Autophagin 1; Autophagy related cysteine endopeptidas |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Pig |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
44 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated Synthesised phosphopeptide derived from human APG4B around the phosphorylation site of Ser34 |
抗原表位 |
KY(p-S)IF |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm (Probable). |
Tissue |
Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas. |
SIMILARITY |
Belongs to the peptidase C54 family. |
Function |
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a reveal |
SWISS |
Q9Y4P1 |
Gene ID |
23192 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
ATG4B is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. |