货号 |
bsm-52059R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Cytokeratin 19 antibody |
中文名称 |
Rabbit Anti-Cytokeratin 19 antibody |
产品标签 |
重组兔单抗 |
研究领域 |
肿瘤,细胞生物,干细胞 |
英文别名 |
40 kDa keratin intermediate filament; CK 19; ck19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type |
反应物种(已验证) |
Human |
反应物种(预测) |
Mouse |
产品应用(已验证) |
WB,IHC,ICC |
产品应用(可推荐) |
IF |
推荐稀释比例 |
WB=1:2000-5000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:20-100,ICC=1:100, |
克隆类型 |
单克隆 |
克隆号 |
2F3 |
抗体来源 |
Rabbit |
理论分子量 |
44 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
Recombinant human Cytokeratin 19 protein, around C-terminal 100aa. |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagu |
SIMILARITY |
Belongs to the intermediate filament family. |
SUBUNIT |
Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein. |
Function |
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
SWISS |
P08727 |
Gene ID |
3880 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008] |