货号 |
bsm-52127R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Peroxiredoxin 1 antibody |
中文名称 |
Rabbit Anti-Peroxiredoxin 1 antibody |
产品标签 |
重组兔单抗 |
研究领域 |
肿瘤,细胞生物,免疫学 |
英文别名 |
Peroxiredoxin-1; Peroxiredoxin 1; Prdx 1; Prdx1; PRDX1_HUMAN; Hbp23; Heme binding 23 kDa protein; Macrophage 23 Kd stress protein; Macrophage 23kDa stress protein; Macrophase stress protein 22kDa; Macrophase stress protein 23 kd; MSP23; Natural killer cel |
反应物种(已验证) |
Human,Mouse |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF |
推荐稀释比例 |
WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200, |
克隆类型 |
单克隆 |
克隆号 |
7A1 |
抗体来源 |
Rabbit |
理论分子量 |
22 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
Recombinant human Peroxiredoxin 1 protein, full length |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. Melanosome. |
SIMILARITY |
Belongs to the AhpC/TSA family.
Contains 1 thioredoxin domain. |
SUBUNIT |
Homodimer; disulfide-linked, upon oxidation. May form heterodimers with AOP2. Interacts with GDPD5; forms a mixed-disulfide with GDPD5 (By similarity). |
Function |
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in |
Post-translational |
Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity. |
SWISS |
Q06830 |
Gene ID |
5052 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]. |