货号 |
bs-22897R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-ATG13 antibody |
中文名称 |
Rabbit Anti-ATG13 antibody |
研究领域 |
肿瘤,新陈代谢,线抗体, |
英文别名 |
ATG13 autophagy related 13 homolog; ATG13_HUMAN; Autophagy related protein 13; Autophagy-related protein 13; FLJ20698; KIAA0652. |
反应物种(已验证) |
Mouse,Rat |
反应物种(预测) |
Human,Chicken,Dog,Pig,Rabbit,Sheep |
产品应用(已验证) |
IHC |
推荐稀释比例 |
IHC-P=1:400-800, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
57 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human ATG13 |
抗原表位 |
41-140/517 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm, cytosol.Preautophagosomal structure. |
SIMILARITY |
Belongs to the ATG13 metazoan family. |
SUBUNIT |
Part of a complex consisting of ATG13, ULK1 and RB1CC1. Interacts with ATG101. Interacts with ULK1 (via C-terminus). Interacts with ULK2 (via C-terminus). |
Function |
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 compl |
Post-translational |
Phosphorylated by ULK1, ULK2 and mTOR. Phosphorylation status depends on nutrient-rich conditions; dephosphorylated during starvation or following treatment with rapamycin. ULK1-mediated phosphorylation of ATG13 at Ser-355 is required for efficient cleara |
SWISS |
O75143 |
Gene ID |
9776 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. |