货号 |
bsm-52251R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-VDAC1(Mitochondrial Loading Control) antibody |
中文名称 |
Rabbit Anti-VDAC1(Mitochondrial Loading Control) antibody |
产品标签 |
内参抗体,重组兔单抗 |
研究领域 |
细胞生物,免疫学,细胞凋亡,通道蛋白,线抗体, |
英文别名 |
voltage-dependent anion channel; hVDAC1; MGC111064; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31 HL; Porin 31HL; Porin 31HM; VDAC 1; VDAC; VDAC1; Voltage dependent anion channel 1; Voltage dependent anion selective channel pr |
反应物种(已验证) |
Human,Mouse,Rat |
产品应用(已验证) |
WB,IHC |
推荐稀释比例 |
WB=1:500-2000,IHC-P=1:400-800, |
克隆类型 |
单克隆 |
克隆号 |
9A7 |
抗体来源 |
Rabbit |
理论分子量 |
32 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Lyophilized or Liquid |
免疫原 |
Recombinant human VDAC1 |
抗原表位 |
1-100/283 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. Endosome membrane; Peripheral membrane protein (Probable). |
SIMILARITY |
Belongs to the VTA1 family. |
SUBUNIT |
Interacts with VPS4B. Interacts with CHMP1B. Interacts with CHMP2A; the interaction probably involves the open conformation of (polymerized) CHMP2A. May interact with CHMP3. Interacts with CHMP5; the interaction involves soluble CHMP5. Interacts with IST1 |
Function |
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation |
SWISS |
P21796 |
Gene ID |
7416 |
保存条件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle. |