货号 |
bsm-54217R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-CSNK2B/CK II beta antibody |
中文名称 |
Rabbit Anti-CSNK2B/CK II beta antibody |
产品标签 |
重组兔单抗 |
研究领域 |
肿瘤,细胞生物,信号转导,干细胞,细胞周期蛋白,转录调节因子,激酶和磷酸酶 |
英文别名 |
Casein kinase 2 beta polypeptide; casein kinase IIβ; Casein kinase II subunit beta; CK II beta; CK2B; CK2N; CSK2B; CSK2B_HUMAN; CSNK 2B; CSNK2B; G5A; MGC138222; MGC138224; Phosvitin; Protein G5a. |
反应物种(已验证) |
Human,Mouse,Rat |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IP |
推荐稀释比例 |
WB=1:500-2000,IP=1:10-50,IHC-P=1:50-100, |
克隆类型 |
单克隆 |
克隆号 |
2C9 |
抗体来源 |
Rabbit |
理论分子量 |
25 |
细胞定位 |
细胞核,细胞浆,细胞膜,细胞外基质,分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human CSNK2B/CK II beta |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SIMILARITY |
Belongs to the casein kinase 2 subunit beta family. |
SUBUNIT |
Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions. Interacts with TCTEX1D3 (By similarity). Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of |
Function |
Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. |
Post-translational |
Phosphorylated by alpha subunit. |
SWISS |
P67871 |
Gene ID |
1460 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008]. |