货号 |
bs-8774R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Histone H3 (CAEEL, Loading Control) antibody |
中文名称 |
Rabbit Anti-Histone H3 (CAEEL, Loading Control) antibody |
英文别名 |
H3_CAEEL; his-2; H3_CAEEL; |
反应物种(预测) |
Caenorhabditis Elegans |
产品应用(已验证) |
WB |
推荐稀释比例 |
WB=1:500-2000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
15 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
Recombinant Caenorhabditis elegans Histone H3. |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. Chromosome. |
SIMILARITY |
Belongs to the histone H3 family. |
SUBUNIT |
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. |
Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replic |
Post-translational |
Phosphorylated at Ser-11 and Ser-29 during M phase. Phosphorylation of Ser-11 requires air-2 but not air-1. Dephosphorylated by gsp-1 and/or gsp-2 during chromosome segregation.
Acetylation is generally linked to gene activation.
Methylation at Ly |
SWISS |
P08898 |
Gene ID |
180074 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |