货号 |
bs-24751R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-ZDHHC3 antibody |
中文名称 |
Rabbit Anti-ZDHHC3 antibody |
研究领域 |
神经生物学,信号转导,细胞膜受体,锌指蛋白,G蛋白信号, |
英文别名 |
DHHC-3; GABA-A receptor-associated membrane protein 1; Golgi-specific DHHC zinc finger protein; Gramp1; Palmitoyltransferase ZDHHC3; Protein DHHC1; ZDHC3; ZDHC3_HUMAN; GODZ; Zinc finger DHHC domain-containing protein 3; Zinc finger protein 373; ZNF373. |
中文别名 |
GODZ |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Pig,Cow,Horse,Rabbit |
产品应用(已验证) |
WB |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
34 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human GODZ |
抗原表位 |
1-100/299 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Golgi apparatus membrane. |
SIMILARITY |
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger. |
Function |
Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads |
Post-translational |
Autopalmitoylated. |
SWISS |
Q9NYG2 |
Gene ID |
51304 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Golgi-specific DHHC (Asp-His-His-Cys) zinc finger protein (GODZ), also known as, Palmitoyltransferase ZDHHC3 or Zinc finger protein 373, is a 327 amino acid protein member of the DHHC palmitoyltransferase family. Localized to the Golgi apparatus membrane, GODZ contains one DHHC-type zinc finger, which is necessary for its palmitoyltransferase activity. GODZ has been implicated in the palmitoylation and regulated trafficking of diverse substrates that function various inhibitory and excitatory synapses. Specifically, it palmitoylates the gamma subunit 2 of GABA(A) receptors, which leads to normal synaptic GABAergic inhibitory function. GODZ also palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. Two isoforms of GODZ exist as a result of alternative splicing events. |