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货号 | bsm-77001M-1 |
品牌 | |
浓度 | |
货期 | 现货 |
英文名称 | Mouse Anti-Albumin(Loading Control, animal-free) antibody |
中文名称 | Mouse Anti-Albumin(Loading Control, animal-free) antibody |
产品标签 | 内参抗体 |
研究领域 | 细胞生物,免疫学 |
英文别名 | ALB; Serum albumin; ALBU_HUMAN; Albumin (32 AA); Albumin (AA 34); Analbuminemia; Bisalbuminemia; Cell growth inhibiting protein 42; DKFZp779N1935; Dysalbuminemic hyperthyroxinemia; Growth inhibiting protein 20; HSA; Hyperthyroxinemia dysalbuminemic; PRO08 |
中文别名 | 人血清白蛋白 |
反应物种(已验证) | Human |
反应物种(预测) | Mouse,Rat,Pig |
产品应用(已验证) | WB |
推荐稀释比例 | WB=1:500-2000, |
克隆类型 | 单克隆 |
克隆号 | 3F4 |
抗体来源 | Mouse |
理论分子量 | 69 |
细胞定位 | 分泌型蛋白 |
性状 | Liquid |
免疫原 | human Serum albumin |
亚型 | IgG |
纯化方法 | affinity purified by Protein A |
SUBCELLULAR | Secreted. |
Tissue | Plasma. |
SIMILARITY | Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. |
Function | Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in pl |
Post-translational | Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylation sites are present in the extracelllular medium. Acetylated on Lys- |
DISEASE | Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemi |
SWISS | P02769 |
Gene ID | 280717 |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 | Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. |