货号 |
bsm-30074M-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Mouse Anti-human CD14 antibody |
中文名称 |
Mouse Anti-human CD14 antibody |
研究领域 |
细胞生物,免疫学,干细胞,细胞表面分子,细胞类型标志物(CD Markers),淋巴细胞, |
英文别名 |
Monocyte Differentiation Antigen 14; CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_HUMAN; Myeloid cell-specific leucine-rich glycoprotein. |
反应物种(预测) |
Human |
克隆类型 |
单克隆 |
克隆号 |
14F4 |
抗体来源 |
Mouse |
理论分子量 |
35/40 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
亚型 |
Mouse IgG1, k |
纯化方法 |
Affinity purified by Protein G |
SUBCELLULAR |
Cell membrane; Lipid-anchor, GPI-anchor. |
SIMILARITY |
Contains 11 LRR (leucine-rich) repeats. |
SUBUNIT |
Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4. |
Function |
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molec |
SWISS |
P08571 |
Gene ID |
929 |
保存条件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010] |