货号 |
bsm-60299R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-XRCC5/Ku80 antibody |
中文名称 |
Rabbit Anti-XRCC5/Ku80 antibody |
产品标签 |
重组兔单抗 |
研究领域 |
肿瘤,转录调节因子 |
英文别名 |
86 kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 2; ATP dependent DNA helicase II 80 kDa subunit; ATP dependent DNA helicase II 86 Kd subunit; ATP dependent DNA helicase II; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helic |
反应物种(已验证) |
Human,Mouse |
产品应用(已验证) |
IHC,ICC |
产品应用(可推荐) |
IF |
推荐稀释比例 |
IHC-P=1:1000,IF=1:50-100,ICC=1:100, |
克隆类型 |
单克隆 |
克隆号 |
K8C2 |
抗体来源 |
Rabbit |
理论分子量 |
83 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human XRCC5/Ku80 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SWISS |
P13010 |
Gene ID |
7520 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |