货号 |
bsm-33874M-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-PLAUR antibody |
中文名称 |
Rabbit Anti-PLAUR antibody |
研究领域 |
肿瘤,心血管,细胞生物,免疫学,信号转导,细胞膜受体 |
英文别名 |
Plasminogen activator,urokinase receptor; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3; U-PAR; U PAR; UPAR; MO3; MO 3; CD 87; CD87; Monocyte activation antigen Mo3; u plasminogen activator receptor; UPA receptor; Urina |
反应物种(已验证) |
Human,Rat |
产品应用(已验证) |
IHC,FCM |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:400-800,Flow Cyt=1ug/Test, |
克隆类型 |
单克隆 |
抗体来源 |
Mouse |
理论分子量 |
31 |
细胞定位 |
细胞膜,分泌型蛋白 |
性状 |
Liquid |
免疫原 |
Recombinant human PLAUR protein |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SWISS |
Q03405 |
Gene ID |
5329 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq]. |