货号 |
bs-0159R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Tubulin-alpha (Loading Control) antibody |
中文名称 |
Rabbit Anti-Tubulin-alpha (Loading Control) antibody |
产品标签 |
内参抗体 |
英文别名 |
Alpha tubulin 1; Alpha-tubulin 1; Detyrosinated alpha Tubulin; FLJ30169; H2 alpha; TBA4A_HUMAN; Testis specific alpha tubulin; Testis-specific alpha-tubulin; TUBA 4A; TUBA1; Tuba4a; Tubulin alpha 1 (testis specific); Tubulin alpha 1; Tubulin alpha 1 chain |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Cow,Sheep |
产品应用(已验证) |
WB,FCM |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:2000-5000,Elisa=1:5000-10000,Flow Cyt=1μg/Test, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
50 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Tubulin-alpha 1 |
抗原表位 |
375-448/448 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm, cytoskeleton. |
SIMILARITY |
Belongs to the tubulin family. |
SUBUNIT |
Dimer of alpha and beta chains. |
Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Post-translational |
Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of fu |
SWISS |
Q71U36 |
Gene ID |
7846 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Tubulin is a major cytoskeleton that has five distinct forms, designated alpha, beta, gamma, delta and epsilon tubulin. The alpha and beta tubulins form a heterodimer that polymerize into the cylindrical microtubule fibers. Both alpha and beta tubulin bind GTP. Only beta tubulin hydrolyzes GTP to GDP. This hydrolysis is a process that is linked to tubulin polymerization and microtubule formation. The alpha tubulin isomer can be modified by addition of a C-terminal tyrosine residue. This modification may influence polymerization rates. The gamma tubulin isomer is localized to centrosomes which compose the heart of the microtubule organizing center from which microtubule fibers emanate. |