货号 |
bs-0016R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Tyrosine Hydroxylase antibody |
中文名称 |
Rabbit Anti-Tyrosine Hydroxylase antibody |
研究领域 |
肿瘤,免疫学,神经生物学,信号转导,新陈代谢,(Neuronal Marker), |
英文别名 |
Tyrosine Hydroxylase; DYT14; DYT5b; ple; Protein Pale; c; The; TYH; Tyrosine 3 hydroxylase; Tyrosine 3 monooxygenase; Tyk2; TY3H_HUMAN; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH. |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Dog,Cow |
产品应用(已验证) |
WB,IHC,IF |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
60 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human TH |
抗原表位 |
101-165/528 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Mainly expressed in the brain and adrenal glands. |
SIMILARITY |
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. |
Function |
Plays an important role in the physiology of adrenergic neurons. |
DISEASE |
Defects in TH are the cause of Segawa syndrome autosomal recessive (ARSEGS) [MIM:605407]. A form of DOPA-responsive dystonia presenting in infancy or early childhood. Dystonia is defined by the presence of sustained involuntary muscle contractions, often |
SWISS |
P07101 |
Gene ID |
7054 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] |