货号 |
bs-0186R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-IRS3 antibody |
中文名称 |
Rabbit Anti-IRS3 antibody |
研究领域 |
细胞生物,神经生物学,信号转导,激酶和磷酸酶,糖尿病,内分泌病,结合蛋白, |
英文别名 |
IRS1--Insulin receptor substrate-3; IRS3; IRS-3; IRS3. |
反应物种(已验证) |
Mouse,Rat,Pig |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
53 |
细胞定位 |
细胞浆,细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from mouse IRS-3 |
抗原表位 |
261-360/494 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SWISS |
O54718 |
Gene ID |
16369 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. |