货号 |
bs-0850R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-S100A1 antibody |
中文名称 |
Rabbit Anti-S100A1 antibody |
研究领域 |
肿瘤,细胞生物,神经生物学 |
英文别名 |
S100; S-100 protein alpha subunit; S-100 protein alpha chain; Protein S100-A1; S100 calcium-binding protein A1; S100 alpha; Protein S100-A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 Calcium Binding Protein A1; S100 calcium-binding prot |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Chicken,Dog,Cow,Horse |
产品应用(已验证) |
FCM |
产品应用(可推荐) |
IHC,IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=1ug/Test,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
10 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human S100A1 |
抗原表位 |
11-94/94 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. |
Tissue |
Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain. |
SIMILARITY |
Belongs to the S-100 family.
Contains 2 EF-hand domains. |
SUBUNIT |
Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. Also forms heterodimers with S100P. Interacts with AGER and CAPZA1. Interacts with FKBP4. Interacts with RYR1 and RYR2. Interacts with CACYBP in a calcium-dependent man |
Function |
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high |
SWISS |
P23297 |
Gene ID |
6271 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008] |