| Mouse Anti-Human PD-1 antibody |
| 产品应用（已验证） |
FCM |
| 产品应用（可尝试） |
WB,ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,Flow Cyt=1:100, |
| 研究领域 |
肿瘤,细胞生物,免疫学,细胞凋亡 |
| 标签 |
Array |
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Blank control:MCF7.
Primary Antibody (green line): Mouse Anti-PD-1 antibody (bsm-41654M)
Dilution: 1：100;
Secondary Antibody : Goat anti-mouse IgG-FITC
Dilution: 0.5ug/Test.
Protocol
The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
RRID：RRID
产品名称：Mouse Anti-Human PD-1 antibody
别名： Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2.
中文名称：人程序性死亡1单克隆抗体
英文名称：Mouse Anti-Human PD-1 antibody
抗体来源： Mouse
克隆类型：单克隆
细胞定位：细胞膜
性 状：Liquid
亚 型：IgG2b
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：Recombinant Human PD-1 Protein
抗原表位：24-170/170
SWISS：Q15116
Gene ID ：5133
Human Gene ID：5133
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Function：Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other fac
Subunit：Monomer.
Subcellular Location：Membrane; Single-pass type I membrane protein.
Tissue Specificity：Ta,Ba,Ma,Thy
DISEASE：Systemic lupus erythematosus 2 (SLEB2) [MIM:605218]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of u
Similarity：Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
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