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货号 | bs-5587R-1 |
品牌 | |
浓度 | |
货期 | 现货 |
英文名称 | Rabbit Anti-phospho-PI 3 Kinase p110 delta (Tyr524) antibody |
中文名称 | Rabbit Anti-phospho-PI 3 Kinase p110 delta (Tyr524) antibody |
产品标签 | 磷酸化抗体 |
研究领域 | 肿瘤,免疫学,信号转导,转录调节因子,激酶和磷酸酶 |
英文别名 | PI 3 Kinase p110 delta (phospho Tyr524); PIK3CD(phospho Y524); PI3 Kinase p110 delta; p110D; p110delta; Phosphatidylinositol 3 kinase catalytic delta polypeptide; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform; Phosphatidyl |
反应物种(已验证) | Human,Mouse,Rat |
反应物种(预测) | Chicken,Dog,Pig,Cow,Horse |
产品应用(已验证) | WB,FCM |
产品应用(可推荐) | IHC,IF,ELISA |
推荐稀释比例 | WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=2ug/Test,IF=1:100-500, |
克隆类型 | 多克隆 |
抗体来源 | Rabbit |
理论分子量 | 115 |
细胞定位 | 细胞浆 |
性状 | Liquid |
免疫原 | KLH conjugated Synthesised phosphopeptide derived from human PIK3CD around the phosphorylation site of Tyr524 |
抗原表位 | EL(p-Y)EH |
亚型 | IgG |
纯化方法 | affinity purified by Protein A |
Tissue | Expressed predominantly in leukocytes. |
SIMILARITY | Belongs to the PI3/PI4-kinase family. Contains 1 C2 PI3K-type domain. Contains 1 PI3K-ABD domain. Contains 1 PI3K-RBD domain. Contains 1 PI3K/PI4K domain. Contains 1 PIK helical domain. |
SUBUNIT | Heterodimer of a catalytic subunit PIK3CD and a p85 regulatory subunit (PIK3R1, PIK3R2 or PIK3R3). Interacts with ERAS. |
SWISS | O00329 |
Gene ID | 5293 |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 | PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p110. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K. Four isoforms of p110 has been found; the alpha, beta, gamma, and the delta subunit. The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain. |