货号 |
bs-3898R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-CYP11B1 antibody |
中文名称 |
Rabbit Anti-CYP11B1 antibody |
研究领域 |
肿瘤,细胞生物,免疫学,染色质和核信号,生长因子和激素,转录调节因子,线抗体, |
英文别名 |
CPN1; CYP11B; CYPXIB1; Cytochrome P450 11B1, mitochondrial; Cytochrome p450 XIB1; Cytochrome P450, family 11, subfamily B, polypeptide 1; FHI; P 450C11; P450C11; S11BH; Steroid 11 beta hydroxylase; Steroid 11 beta monooxygenase; C11B1_HUMAN; Cytochrome P- |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
IHC,IF |
产品应用(可推荐) |
WB,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
55 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human CYP11B1 |
抗原表位 |
301-400/503 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
Tissue |
Mitochondrion membrane. |
SIMILARITY |
Belongs to the cytochrome P450 family. |
Function |
Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB. |
DISEASE |
Defects in CYP11B1 are the cause of adrenal hyperplasia type 4 (AH4) [MIM:202010]. AH4 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by andro |
SWISS |
P15538 |
Gene ID |
1584 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB. |