免 疫 原：KLH conjugated synthetic peptide derived from human CYP11B1
抗原表位：301-400/503
SWISS：P15538
Gene ID ：1584
Human Gene ID：1584

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
Function：Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
Tissue Specificity：Mitochondrion membrane.
DISEASE：Defects in CYP11B1 are the cause of adrenal hyperplasia type 4 (AH4) [MIM:202010]. AH4 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by andro
Similarity：Belongs to the cytochrome P450 family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.