货号 |
bs-1910R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-TGF beta Receptor III antibody |
中文名称 |
Rabbit Anti-TGF beta Receptor III antibody |
研究领域 |
肿瘤,细胞生物,免疫学,神经生物学,信号转导,干细胞,细胞凋亡,生长因子和激素,激酶和磷酸酶 |
英文别名 |
Beta glycan; TGF Beta R3; Betaglycan; Betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor B |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Chicken,Dog,Pig,Sheep |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
94 |
细胞定位 |
细胞膜,细胞外基质,分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human TGFBR3 |
抗原表位 |
701-850/850 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. |
SIMILARITY |
Contains 1 ZP domain. |
SUBUNIT |
Interacts with TCTEX1D4. |
Function |
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. |
Post-translational |
Extensively modified by glycosaminoglycan groups (GAG). |
SWISS |
Q03167 |
Gene ID |
7049 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]. |