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Rabbit Anti-TGF beta Receptor III antibody
多克隆  |   SKU:bs-1910R

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货号:bs-3351R
¥1280
订购号:bs-1910R
¥1098.00-2900.00
货期:现货
Rabbit Anti-TGF beta Receptor III antibody
反应物种(预测)

Chicken,Dog,Pig,Sheep

产品应用(已验证)

WB,IHC

产品应用(可尝试)

IF,ELISA

推荐稀释比例

WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,

研究领域

肿瘤,细胞生物,免疫学,神经生物学,信号转导,干细胞,细胞凋亡,生长因子和激素,激酶和磷酸酶

标签

Array

  • Sample:
    K562 Cell (Human) Lysate at 40 ug
    HepG2 Cell (Human) Lysate at 40 ug
    Hela Cell (Human) Lysate at 40 ug
    Primary: Anti- TGF beta Receptor III (bs-1910R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 94 kD
    Observed band size: 110 kD
  • Independently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (bs-1910R) at 1:250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining

产品信息

RRID:AB_10883836
产品名称:Rabbit Anti-TGF beta Receptor III antibody
别名: Beta glycan; TGF Beta R3; Betaglycan; Betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor B
中文名称:转移生长因子β受体3抗体
英文名称:Rabbit Anti-TGF beta Receptor III antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞膜,细胞外基质,分泌型蛋白
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

免疫原信息

免 疫 原:KLH conjugated synthetic peptide derived from human TGFBR3
抗原表位:701-850/850
SWISS:Q03167
Gene ID :7049
Human Gene ID:7049

产品介绍

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010].
Function:Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Subunit:Interacts with TCTEX1D4.
Subcellular Location:Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Post-translational modifications:Extensively modified by glycosaminoglycan groups (GAG).
Similarity:Contains 1 ZP domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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