货号 |
bs-0931R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Histone H1.4 (Acetyl K53) antibody |
中文名称 |
Rabbit Anti-Histone H1.4 (Acetyl K53) antibody |
产品标签 |
乙酰化抗体 |
研究领域 |
肿瘤,发育生物学,信号转导,细胞凋亡,转录调节因子,表观遗传学, |
英文别名 |
Histone H1.4(Ac-Lys53); Histone H1b (Ac-Lys53); Acetyl-Histone H1.4 (Lys53); Acetyl-Histone H1.4 (K53); HIST1H1E; H1F4; Histone H1.4; Histone H1b; H14_HUMAN; Histone H1s-4; H1 histone family member 4; H1E; Hist1h1e; Histone 1 H1e; Histone cluster 1 H1e; H |
反应物种(已验证) |
Human,Mouse,Rat |
反应物种(预测) |
Dog,Pig,Cow,Horse |
产品应用(已验证) |
IHC,FCM |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=1ug/test,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
24 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated Synthesised acetylpeptide derived from human Histone H1b around the acetylation site of Lys53 |
抗原表位 |
AS(Ac-K)ER |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. Chromosome. |
SIMILARITY |
Belongs to the histone H1/H5 family. Contains 1 H15 (linker histone H1/H5 globular) domain. |
Function |
Histones H1 are necessary for the condensation of nucleosome chains into higher order structures. |
Post-translational |
Acetylated at Lys-26. Deacetylated at Lys-26 by SIRT1. |
SWISS |
P10412 |
Gene ID |
3008 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. |