货号 |
bs-3818R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-GDF15 antibody |
中文名称 |
Rabbit Anti-GDF15 antibody |
研究领域 |
心血管,细胞生物,信号转导,细胞周期蛋白,细胞分化, |
英文别名 |
GDF 15;
GDF-15;
GDF15_HUMAN;
Growth differentiation factor 15;
Growth/differentiation factor 15;
Macrophage inhibitory cytokine 1;
MIC 1;
Mic-1;
MIC1;
NAG 1;
NAG-1;
NAG1;
NRG 1;
NRG-1;
NRG1;
NSAID (nonsteroidal anti inflammatory drug) acti |
反应物种(已验证) |
Human,Mouse,Rat |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
12.5/34 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human GDF-15 |
抗原表位 |
221-308/308 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. |
Tissue |
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. |
SIMILARITY |
Belongs to the TGF-beta family. |
SWISS |
Q99988 |
Gene ID |
9518 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects.
BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.
GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53. |