货号 |
bs-1196R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-PAR4 antibody |
中文名称 |
Rabbit Anti-PAR4 antibody |
研究领域 |
细胞生物,信号转导,激酶和磷酸酶,细胞膜受体 |
英文别名 |
F2RL3;
F2R Like Thrombin/Trypsin Receptor 3;
Coagulation Factor II (Thrombin) Receptor-Like 3;
Thrombin Receptor-Like 3;
PAR-4;
Coagulation Factor II Receptor-Like 3;
Proteinase-Activated Receptor-4;
Proteinase-Activated Receptor 4;
Protease-Activ |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse,Dog,Pig,Cow,Horse,GuineaPig |
产品应用(可推荐) |
IHC,IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
41 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Proteinase-activated receptor 4 |
抗原表位 |
301-385/385 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell membrane; Multi-pass membrane protein. |
Tissue |
Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets. |
SIMILARITY |
Belongs to the G-protein coupled receptor 1 family. |
Function |
Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. |
Post-translational |
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. |
SWISS |
Q96RI0 |
Gene ID |
9002 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008] |