货号 |
bs-6730R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-Upstream Binding Protein 1 antibody |
中文名称 |
Rabbit Anti-Upstream Binding Protein 1 antibody |
研究领域 |
肿瘤,细胞生物,信号转导,转录调节因子,结合蛋白,表观遗传学, |
英文别名 |
LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN. |
反应物种(已验证) |
Mouse |
反应物种(预测) |
Human,Rat,Chicken,Dog,Pig,Cow,Horse |
产品应用(已验证) |
WB |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
60 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1 |
抗原表位 |
351-450/540 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. |
Tissue |
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines. |
SIMILARITY |
Belongs to the grh/CP2 family. CP2 subfamily. |
SUBUNIT |
Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1. |
Function |
UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells. |
SWISS |
Q9NZI7 |
Gene ID |
7342 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |