| Rabbit Anti-Upstream Binding Protein 1 antibody |
| 反应物种（预测） |
Human,Rat,Chicken,Dog,Pig,Cow,Horse |
| 产品应用（已验证） |
WB |
| 产品应用（可尝试） |
ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
| 研究领域 |
肿瘤,细胞生物,信号转导,转录调节因子,结合蛋白,表观遗传学, |
| 标签 |
Array |
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Sample:
Pancreas (Mouse) Lysate at 40 ug
Primary: Anti- Upstream Binding Protein 1 (bs-6730R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 56 kD
RRID：AB_11068767
产品名称：Rabbit Anti-Upstream Binding Protein 1 antibody
别名： LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.
中文名称：上游结合蛋白1抗体
英文名称：Rabbit Anti-Upstream Binding Protein 1 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞核
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1
抗原表位：351-450/540
SWISS：Q9NZI7
Gene ID ：7342
Human Gene ID：7342
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
Function：UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.
Subunit：Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.
Subcellular Location：Nucleus.
Tissue Specificity：Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.
Similarity：Belongs to the grh/CP2 family. CP2 subfamily.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
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