货号 |
bs-7767R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-phospho-RACGAP1 (Ser387) antibody |
中文名称 |
Rabbit Anti-phospho-RACGAP1 (Ser387) antibody |
产品标签 |
磷酸化抗体 |
研究领域 |
细胞生物,信号转导,转录调节因子,细胞分化, |
英文别名 |
RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387); GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1. |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat,Dog,Cow |
产品应用(已验证) |
WB |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
71 |
细胞定位 |
细胞核,细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387 |
抗原表位 |
RI(p-S)GC |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. |
Tissue |
Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated |
SIMILARITY |
Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Rho-GAP domain. |
SUBUNIT |
Heterotetramer of two molecules each of RACGAP1 and KIF23. |
SWISS |
Q9H0H5 |
Gene ID |
29127 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases. |