Rabbit Anti-phospho-RACGAP1 (Ser387) antibody |
反应物种(预测) |
Rat,Dog,Cow |
产品应用(已验证) |
WB |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
研究领域 |
细胞生物,信号转导,转录调节因子,细胞分化, |
标签 |
Array |
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Sample:
Lung (Mouse) Lysate at 40 ug
A431(Human) Cell Lysate at 30 ug
A549(Human) Cell Lysate at 30 ug
HL60(Human) Cell Lysate at 30 ug
Hela(Human) Cell Lysate at 30 ug
RRID:RRID
产品名称:Rabbit Anti-phospho-RACGAP1 (Ser387) antibody
别名: RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387); GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.
中文名称:磷酸化Rho GTP酶激活蛋白GAP抗体
英文名称:Rabbit Anti-phospho-RACGAP1 (Ser387) antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞核,细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387
抗原表位:RI(p-S)GC
SWISS:Q9H0H5
Gene ID :29127
Human Gene ID:29127
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Subunit:Heterotetramer of two molecules each of RACGAP1 and KIF23.
Subcellular Location:Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Tissue Specificity:Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated
Similarity:Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Rho-GAP domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.