货号 |
bs-2396R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-GNMT antibody |
中文名称 |
Rabbit Anti-GNMT antibody |
研究领域 |
信号转导,新陈代谢, |
英文别名 |
EC 2.1.1.20;
Epididymis secretory sperm binding protein Li 182mP;
Glycine N methyltransferase;
Glycine N-methyltransferase;
GNMT_HUMAN;
HEL S 182mP;
OTTHUMP00000016412. |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse,Dog,Pig,Cow,Horse |
产品应用(已验证) |
IHC |
产品应用(可推荐) |
WB,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
32 |
细胞定位 |
细胞浆 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human GNMT |
抗原表位 |
51-150/295 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cytoplasm. |
Tissue |
Abundant in liver. |
SIMILARITY |
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. |
SUBUNIT |
Homotetramer. |
Function |
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet a |
DISEASE |
Defects in GNMT are the cause of glycine N-methyltransferase deficiency (GNMT deficiency) [MIM:606664]; also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum |
SWISS |
Q14749 |
Gene ID |
27232 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
GNMT catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). It plays a possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. |