免 疫 原：KLH conjugated synthetic peptide derived from human GNMT
抗原表位：51-150/295
SWISS：Q14749
Gene ID ：27232
Human Gene ID：27232

GNMT catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). It plays a possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Function：Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet a
Subunit：Homotetramer.
Subcellular Location：Cytoplasm.
Tissue Specificity：Abundant in liver.
DISEASE：Defects in GNMT are the cause of glycine N-methyltransferase deficiency (GNMT deficiency) [MIM:606664]; also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum
Similarity：Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.