货号 |
bs-12580R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-BDP antibody |
中文名称 |
Rabbit Anti-BDP antibody |
研究领域 |
肿瘤,发育生物学,神经生物学,干细胞,细胞周期蛋白,表观遗传学, |
英文别名 |
BDP / ARID3B; ARI3B_HUMAN; ARID domain containing protein 3B; ARID domain-containing protein 3B; Arid3b; AT rich interactive domain 3B BRIGHT like; AT rich interactive domain containing protein 3B; AT-rich interactive domain-containing protein 3B; Bright |
反应物种(已验证) |
Human |
反应物种(预测) |
Mouse,Rat,Dog,Horse,Rabbit |
产品应用(已验证) |
WB |
产品应用(可推荐) |
IHC,ICC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
61 |
细胞定位 |
细胞核 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human BDP/ARID3B |
抗原表位 |
251-350/561 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Nucleus. |
Tissue |
Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level). |
SIMILARITY |
Contains 1 ARID domain.
Contains 1 REKLES domain. |
SUBUNIT |
Heterodimer with ARID3A. Interacts with unphosphorylated RB1. |
Function |
Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. |
SWISS |
Q8IVW6 |
Gene ID |
10620 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma. |