货号 |
bs-18877R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-RSPO3 antibody |
中文名称 |
Rabbit Anti-RSPO3 antibody |
研究领域 |
细胞生物,发育生物学,干细胞 |
英文别名 |
CRISTIN1;
hPWTSR;
hRspo3;
Protein with TSP type-1 repeat;
PWTSR;
R-spondin 3 homolog;
R-spondin-3 [Precursor];
R-spondin-3;
Roof plate specific spondin-3;
Roof plate-specific spondin-3;
RSPO3_HUMAN;
Thrombospondin type I domain containing 2;
T |
反应物种(已验证) |
Human |
反应物种(预测) |
Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,GuineaPig,Cat |
产品应用(已验证) |
WB |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
31 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human RSPO3 |
抗原表位 |
22-100/272 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. |
Tissue |
Ubiquitously expressed. Expressed at higher level in placenta, small intestine, fetal thymus and lymph node. |
SIMILARITY |
Belongs to the R-spondin family.
Contains 2 FU (furin-like) repeats.
Contains 1 TSP type-1 domain. |
Function |
Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway th |
SWISS |
Q9BXY4 |
Gene ID |
84870 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] |