Rabbit Anti-RSPO3 antibody |
反应物种(预测) |
Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,GuineaPig,Cat |
产品应用(已验证) |
WB |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
研究领域 |
细胞生物,发育生物学,干细胞 |
标签 |
Array |
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Sample:
Lane 1: Human Hela cell lysates
Lane 2: Human Lovo cell lysates
Lane 3: Human A549 cell lysates
Lane 4: Human Huvec cell lysates
Primary: Anti-RSPO3 (bs-18877R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kD
Observed band size: 31 kD
RRID:RRID
产品名称:Rabbit Anti-RSPO3 antibody
别名: CRISTIN1;
hPWTSR;
hRspo3;
Protein with TSP type-1 repeat;
PWTSR;
R-spondin 3 homolog;
R-spondin-3 [Precursor];
R-spondin-3;
Roof plate specific spondin-3;
Roof plate-specific spondin-3;
RSPO3_HUMAN;
Thrombospondin type I domain containing 2;
T
中文名称:RSPO3蛋白抗体
英文名称:Rabbit Anti-RSPO3 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:分泌型蛋白
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human RSPO3
抗原表位:22-100/272
SWISS:Q9BXY4
Gene ID :84870
Human Gene ID:84870
This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
Function:Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway th
Subcellular Location:Secreted.
Tissue Specificity:Ubiquitously expressed. Expressed at higher level in placenta, small intestine, fetal thymus and lymph node.
Similarity:Belongs to the R-spondin family.
Contains 2 FU (furin-like) repeats.
Contains 1 TSP type-1 domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.