货号 |
bsm-52009R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-ADAM17 (9E7) antibody |
中文名称 |
Rabbit Anti-ADAM17 (9E7) antibody |
产品标签 |
重组兔单抗 |
研究领域 |
肿瘤,免疫学,神经生物学,信号转导,转录调节因子 |
英文别名 |
A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Fa |
反应物种(已验证) |
Human,Mouse |
反应物种(预测) |
Rat |
产品应用(已验证) |
WB |
产品应用(可推荐) |
IHC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:20-200,IHC-F=1:20-200,IF=1:20-200, |
克隆类型 |
单克隆 |
克隆号 |
9E7 |
抗体来源 |
Rabbit |
理论分子量 |
93 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
Recombinant human ADAM17 protein |
抗原表位 |
700-824/824 |
抗原细胞定位 |
Cytoplasmic |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Membrane. |
Tissue |
Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney. |
SIMILARITY |
Contains 1 disintegrin domain.
Contains 1 peptidase M12B domain. |
SUBUNIT |
Interacts with MAD2L1, MAPK14 and MUC1. |
SWISS |
P78536 |
Gene ID |
6868 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq]. |