货号 |
bsm-60015R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-BMP6 antibody |
中文名称 |
Rabbit Anti-BMP6 antibody |
产品标签 |
重组兔单抗 |
研究领域 |
细胞生物,免疫学,生长因子和激素,转录调节因子 |
英文别名 |
Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; BMP 6; BMP-6; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related (TGFB related) cytokine; Vg related sequence; VGR; VGR1; BMP6_HUMAN. |
中文别名 |
VGR; VGR1 |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse |
产品应用(已验证) |
WB,ICC |
产品应用(可推荐) |
IF |
推荐稀释比例 |
WB=1:500-1000,IF=1:50,ICC=1:50, |
克隆类型 |
单克隆 |
抗体来源 |
Rabbit |
理论分子量 |
56 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human BMP6 |
亚型 |
IgG/Kappa |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. |
Tissue |
Expressed in the lung. Low levels seen in the kidney. |
SIMILARITY |
Belongs to the TGF-beta family. |
SUBUNIT |
Interacts with SOSTDC1. |
Function |
Induces cartilage and bone formation. |
SWISS |
P22004 |
Gene ID |
654 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016] |