Rabbit Anti-BMP6 antibody,蛋白Marker-蛋白检测试剂盒-IVD原料-北京博奥森生物技术有限公司

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重组兔单抗

Rabbit Anti-BMP6 antibody

单克隆 | SKU：bsm-60015R

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货号:bs-3351R

￥1280

50μg

RMB1280

100μg

RMB1980

200μg

RMB2980

支持数据
产品信息
免疫原信息
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订购号:bsm-60015R

￥1580.00-2680.00

50ul

100ul

货期：现货

售后保障

Rabbit Anti-BMP6 antibody
反应物种（预测）	Mouse
产品应用（已验证）	WB,ICC
产品应用（可尝试）	IF
推荐稀释比例	WB=1:500-1000,IF=1:50,ICC=1:50,
研究领域	细胞生物,免疫学,生长因子和激素,转录调节因子
标签	Array

SHSY5Y cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (BMP6) monoclonal Antibody, Unconjugated (bsm-60015R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
Blocking buffer: 5% NFDM/TBST
Primary ab dilution: 1:1000
Primary ab incubation condition: 2 hours at room temperature
Secondary ab: Goat Anti-Rabbit IgG H&L (HRP)
Lysate: A549, SH-SY5Y, N2a, Rat lung
Protein loading quantity: 20 μg
Exposure time: 1 s
Predicted MW: 42 kDa
Observed MW: 42 kDa
Cell line: NIH/3T3 Fixative: 4% Paraformaldehyde Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Rabbit IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for bsm-60015R
Cell line: U-2 OS Fixative: 100% Ice-cold methanol Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Rabbit IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for bsm-60015R

产品信息

RRID：RRID
产品名称：Rabbit Anti-BMP6 antibody
别名： Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; BMP 6; BMP-6; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related (TGFB related) cytokine; Vg related sequence; VGR; VGR1; BMP6_HUMAN.
中文名称：骨形态发生蛋白6重组兔单克隆抗体
英文名称：Rabbit Anti-BMP6 antibody
中文别名：VGR; VGR1
抗体来源： Rabbit
克隆类型：单克隆
细胞定位：分泌型蛋白
性状：Liquid
亚型：IgG/Kappa
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

免疫原信息

免疫原：KLH conjugated synthetic peptide derived from human BMP6
SWISS：P22004
Gene ID ：654
Human Gene ID：654

产品介绍

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
Function：Induces cartilage and bone formation.
Subunit：Interacts with SOSTDC1.
Subcellular Location：Secreted.
Tissue Specificity：Expressed in the lung. Low levels seen in the kidney.
Similarity：Belongs to the TGF-beta family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.