货号 |
bsm-41670M-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Mouse Anti-Prostate Specific Antigen antibody |
中文名称 |
Mouse Anti-Prostate Specific Antigen antibody |
研究领域 |
肿瘤 |
英文别名 |
antigen, prostate-specific; APS; Gamma seminoprotein; Gamma-seminoprotein; hK3; Kallikrein 3; Kallikrein 3, (prostate specific antigen); Kallikrein related peptidase 3; Kallikrein-3; KLK 3; KLK2A1; KLK3; KLK3_HUMAN; P 30 antigen; P-30 antigen; P30 antigen |
反应物种(已验证) |
Human |
产品应用(已验证) |
WB,IHC |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:400-800, |
克隆类型 |
单克隆 |
克隆号 |
4C4 |
抗体来源 |
Mouse |
理论分子量 |
23 |
细胞定位 |
分泌型蛋白 |
性状 |
Liquid |
免疫原 |
Prostate Specific Antigen (PSA) Antigen, Native |
亚型 |
IgG1 |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Secreted. |
Tissue |
Prostate. |
SIMILARITY |
Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. |
SUBUNIT |
Forms heterodimer with SERPINA5. |
Function |
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. |
SWISS |
P07288 |
Gene ID |
354 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. |