货号 |
bs-0528R-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Rabbit Anti-CD24 antibody |
中文名称 |
Rabbit Anti-CD24 antibody |
研究领域 |
肿瘤,细胞生物,免疫学,神经生物学,干细胞,细胞粘附分子,细胞表面分子,糖蛋白,T-淋巴细胞,B-淋巴细胞,骨髓细胞, |
英文别名 |
Signal transducer CD24; CD 24; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 antigen; CD24 molecule; CD24A; GPI linked surface mucin; Heat stable antigen; HSA; Nectadrin; Small cell lung carcinoma cluster 4 antigen; Ly-52; CD24_HUMAN. |
反应物种(已验证) |
Human,Rat |
反应物种(预测) |
Mouse |
产品应用(已验证) |
WB,FCM |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,Flow Cyt=1μg /test, |
克隆类型 |
多克隆 |
抗体来源 |
Rabbit |
理论分子量 |
8 |
细胞定位 |
细胞膜 |
性状 |
Liquid |
免疫原 |
KLH conjugated synthetic peptide derived from human CD24 Propeptide |
抗原表位 |
60-80/80 |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein A |
SUBCELLULAR |
Cell membrane. |
Tissue |
B-cells. Expressed in a number of B-cell lines including P32/SH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells. |
SIMILARITY |
Belongs to the CD24 family. |
Function |
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B- |
Post-translational |
Extensively O-glycosylated. |
DISEASE |
Genetic variations in CD24 are associated with susceptibility to multiple sclerosis (MS). A multifactorial, inflammatory, demyelinating disease of the central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes an |
SWISS |
P25063 |
Gene ID |
100133941 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. The encoded protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. [provided by RefSeq, Jul 2008]. |