货号 |
bsm-2022M-1 |
品牌 |
|
浓度 |
|
货期 |
现货 |
英文名称 |
Mouse Anti-HBeAg antibody |
中文名称 |
Mouse Anti-HBeAg antibody |
研究领域 |
免疫学,细菌及病毒, |
英文别名 |
External core antigen; Precore protein; p25; C; HBEAG_HBVD3; |
反应物种(预测) |
HBV |
产品应用(已验证) |
WB |
产品应用(可推荐) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
克隆类型 |
单克隆 |
克隆号 |
2E9 |
抗体来源 |
Mouse |
理论分子量 |
18 |
性状 |
Liquid |
免疫原 |
HBeAg full length protein |
亚型 |
IgG |
纯化方法 |
affinity purified by Protein G |
SUBCELLULAR |
Secreted. Host nucleus. |
SIMILARITY |
Belongs to the orthohepadnavirus precore antigen family. |
SUBUNIT |
Homodimerizes. |
Function |
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during pe |
Post-translational |
Phosphorylated. Cleaved by host furin. |
SWISS |
P0C573 |
保存条件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Important Note |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
英文介绍 |
Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful. |